Harmonizome 3.0

secretin

This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sct in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the SCT ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for SCT from the Pathway Commons Protein-Protein Interactions dataset.

From GAD Gene-Disease Associations

genes associated with the disease survival after allogeneic sct in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.