Harmonizome 3.0

suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)

The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term st13 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for ST13 from the MSigDB Cancer Gene Co-expression Modules dataset.

From NURSA Protein-Protein Interactions

interacting proteins for ST13 from the NURSA Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for ST13 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the ST13 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.