Harmonizome 3.0

small nucleolar RNA, H/ACA box 16A

Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Mar 2025]

abhydrolase domain containing 16A

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]

protein phosphatase 1, regulatory subunit 16A

Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while the phosphorylation of other MYPT members results in PP1c inactivation, phosphorylation of the encoded protein by protein kinase A results in PP1c activation. [provided by RefSeq, Jan 2020]

leucine rich repeat containing 16A

Involved in several processes, including actin filament network formation; plasma membrane bounded cell projection organization; and positive regulation of cellular component organization. Located in several cellular components, including lamellipodium; macropinosome; and nuclear speck. [provided by Alliance of Genome Resources, Mar 2025]

From HMDB Metabolites of Enzymes

interacting proteins for the 16a-Hydroxydehydroisoandrosterone metabolite from the curated HMDB Metabolites of Enzymes dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the compound 16a [PMID: 14697765] ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the 16a-Hydroxyestrone metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the 16a-Hydroxyandrost-4-ene-3,17-dione metabolite from the curated HMDB Metabolites of Enzymes dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein phosphatase 1, regulatory subunit 16A/B protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Abhydrolase domain-containing protein 16A protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Leucine-rich repeat-containing protein 16A protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From DeepCoverMOA Drug Mechanisms of Action

proteins with high or low expression in SMI-16a relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.

From DGIdb Drug Targets 2026

interacting proteins for the COMPOUND 16A [PMID: 14697765] drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the COMPOUND 16A [PMID: 38522114] drug from theDGIdb Drug Targets 2026 dataset.