Harmonizome 3.0

malonyl CoA:ACP acyltransferase (mitochondrial)

The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]

3-oxoacyl-ACP synthase, mitochondrial

This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]

oleoyl-ACP hydrolase

Enables fatty acyl-[ACP] hydrolase activity. Involved in medium-chain fatty acid biosynthetic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

From DrugBank Drug Targets

interacting proteins for the ACP-103 drug from the curated DrugBank Drug Targets dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Malonyl-CoA ACP transacylase, ACP-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From DrugBank Drug Targets

interacting proteins for the ACP-104 drug from the curated DrugBank Drug Targets dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term acp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Molecular Function Annotations 2015

genes performing the acp phosphopantetheine attachment site binding involved in fatty acid biosynthetic process molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the acp phosphopantetheine attachment site binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Acyl carrier protein (ACP) protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From GO Molecular Function Annotations 2025

genes performing the fatty acyl-[ACP] hydrolase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the ACP-001 drug from theDGIdb Drug Targets 2026 dataset.