Harmonizome 3.0

argonaute RISC catalytic component 2

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ago2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein AGO2 from the curated Hub Proteins Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for AGO2 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the AGO2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the TRBP containing complex (DICER, TRBP, AGO2, RPL7A, EIF6, MOV10) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the AGO2-FXR1-TNF(alpha)ARE-RNP complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the DICER1-NCOA6-AGO2 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TTP-AGO2 complex protein complex from the CORUM Protein Complexes dataset.