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AMOTL1 Geneangiomotin like 1 The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
AMOTL2 Geneangiomotin like 2 Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
AMOT Geneangiomotin This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Angiomotin, C-terminal Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Angiomotin, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Angiomotin isoform p80-Angiostatin complex Gene Setproteins in the Angiomotin isoform p80-Angiostatin complex protein complex from the CORUM Protein Complexes dataset. |
angiomotin Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term angiomotin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Angiomotin Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Angiomotin protein domain from the InterPro Predicted Protein Domain Annotations dataset. |