Harmonizome 3.0

ubiquitin protein ligase E3 component n-recognin 4

The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein. [provided by RefSeq, Aug 2010]

From NURSA Protein Complexes

proteins in the BL3061 (UBR4) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ubr4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the E3 ubiquitin ligase, UBR4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for UBR4 from the Pathway Commons Protein-Protein Interactions dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the UBR4-associated neurodevelopmental syndrome phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the UBR4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.