Harmonizome 3.0

cell division cycle 37

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc37 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cdc37 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From NURSA Protein-Protein Interactions

interacting proteins for CDC37 from the NURSA Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC37 from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the CDC37 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the CDC37 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the CDC37-HSP90AA1-HSP90AB1-MAP3K11 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the HSP90-CDC37-LRRK2 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the IKBKB-CDC37-KIAA1967-HSP90AB1-HSP90AA1 complex protein complex from the CORUM Protein Complexes dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cdc37, Hsp90 binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cdc37, N-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cdc37, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the HSP90-CDC37 chaperone complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the HSP90-CDC37 chaperone complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.