Name

CEP170 Gene

centrosomal protein 170kDa

The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

cep170 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cep170 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CEP170 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for CEP170 from the NURSA Protein-Protein Interactions dataset.

CEP170 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CEP170 from the Pathway Commons Protein-Protein Interactions dataset.

CEP170 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the CEP170 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

CEP170 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the CEP170 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

CEP170, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CEP170, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

BL4464 (CEP170) Gene Set

From NURSA Protein Complexes

proteins in the BL4464 (CEP170) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.