| Name |
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CLEC7A GeneC-type lectin domain family 7, member A This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] |
CLEC7A Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for CLEC7A from the Pathway Commons Protein-Protein Interactions dataset. |
CLEC7A Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the CLEC7A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
CLEC7A (Dectin-1) induces NFAT activation Gene Setproteins participating in the CLEC7A (Dectin-1) induces NFAT activation pathway from the Reactome Pathways 2024 dataset. |
CLEC7A (Dectin-1) signaling Gene Setproteins participating in the CLEC7A (Dectin-1) signaling pathway from the Reactome Pathways 2024 dataset. |
CLEC7A/inflammasome pathway Gene Setproteins participating in the CLEC7A/inflammasome pathway pathway from the Reactome Pathways 2024 dataset. |