Name

CLEC7A Gene

C-type lectin domain family 7, member A

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

CLEC7A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CLEC7A from the Pathway Commons Protein-Protein Interactions dataset.

CLEC7A Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the CLEC7A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

CLEC7A (Dectin-1) induces NFAT activation Gene Set

From Reactome Pathways 2024

proteins participating in the CLEC7A (Dectin-1) induces NFAT activation pathway from the Reactome Pathways 2024 dataset.

CLEC7A (Dectin-1) signaling Gene Set

From Reactome Pathways 2024

proteins participating in the CLEC7A (Dectin-1) signaling pathway from the Reactome Pathways 2024 dataset.

CLEC7A/inflammasome pathway Gene Set

From Reactome Pathways 2024

proteins participating in the CLEC7A/inflammasome pathway pathway from the Reactome Pathways 2024 dataset.