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FBXL20 GeneF-box and leucine-rich repeat protein 20 Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
FBXL20 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for FBXL20 from the Pathway Commons Protein-Protein Interactions dataset. |
FBXL20 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the FBXL20 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
Ubiquitin E3 ligase (Fbxl20, Skp1, Cul1) Gene Setproteins in the Ubiquitin E3 ligase (Fbxl20, Skp1, Cul1) protein complex from the CORUM Protein Complexes dataset. |