Name

LETM1 Gene

leucine zipper-EF-hand containing transmembrane protein 1

This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq, Oct 2009]

letm1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term letm1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

LETM1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LETM1 from the Pathway Commons Protein-Protein Interactions dataset.

LETM1 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the LETM1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

LETM1-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the LETM1-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.