MUTYH

Filters:

Results for "MUTYH": 1 gene, 7 gene sets

Name
MUTYH Gene mutY homolog This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
mutyh Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term mutyh in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
MUTYH Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for MUTYH from the Pathway Commons Protein-Protein Interactions dataset.
MUTYH Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the MUTYH gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
Mutyh-Associate Polyposis Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Mutyh-Associate Polyposis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Defective Base Excision Repair Associated with MUTYH Gene Set From Reactome Pathways 2024 proteins participating in the Defective Base Excision Repair Associated with MUTYH pathway from the Reactome Pathways 2024 dataset.
Defective MUTYH substrate binding Gene Set From Reactome Pathways 2024 proteins participating in the Defective MUTYH substrate binding pathway from the Reactome Pathways 2024 dataset.
Defective MUTYH substrate processing Gene Set From Reactome Pathways 2024 proteins participating in the Defective MUTYH substrate processing pathway from the Reactome Pathways 2024 dataset.