Name

NFU1 Gene

NFU1 iron-sulfur cluster scaffold

This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

NFU1P1 Gene

NFU1 iron-sulfur cluster scaffold pseudogene 1

NFU1P2 Gene

NFU1 iron-sulfur cluster scaffold pseudogene 2

nfu1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nfu1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NFU1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NFU1 from the Pathway Commons Protein-Protein Interactions dataset.

NFU1 iron-sulfur cluster scaffold homologue Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NFU1 iron-sulfur cluster scaffold homologue protein domain from the InterPro Predicted Protein Domain Annotations dataset.