Name

NPY Gene

neuropeptide Y

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]

NPY2R Gene

neuropeptide Y receptor Y2

NPY1R Gene

neuropeptide Y receptor Y1

This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]

NPY4R Gene

neuropeptide Y receptor Y4

NPY6R Gene

neuropeptide Y receptor Y6 (pseudogene)

NPY5R Gene

neuropeptide Y receptor Y5

npy Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term npy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NPY Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the NPY ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

NPY Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NPY from the Pathway Commons Protein-Protein Interactions dataset.

npy2r Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term npy2r in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

npyy Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term npyy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

npy1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term npy1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

npy335 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term npy335 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

npy5r Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term npy5r in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

npy1r Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term npy1r in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NPY-(2-36) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(2-36) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

C2-NPY (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the C2-NPY (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[D-Trp32]NPY Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [D-Trp32]NPY ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Leu31 Pro34]NPY Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Leu31 Pro34]NPY ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Leu31 Pro34]NPY (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Leu31 Pro34]NPY (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(13-36) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(13-36) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(22-36) (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(22-36) (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[125I]NPY Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [125I]NPY ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ala31 Aib32]NPY Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ala31 Aib32]NPY ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[125I][PP1-17 Ala31 Aib32]NPY (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [125I][PP1-17 Ala31 Aib32]NPY (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(16-36) (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(16-36) (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[125I][cPP(1-7) NPY(19-23) Ala31 Aib32 Gln34]hPP Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [125I][cPP(1-7) NPY(19-23) Ala31 Aib32 Gln34]hPP ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(26-36) (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(26-36) (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[125I][Leu31 Pro34]NPY Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [125I][Leu31 Pro34]NPY ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(18-36) (human pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(18-36) (human pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(3-36) (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(3-36) (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Pro34]NPY Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Pro34]NPY ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[PP1-17 Ala31 Aib32]NPY (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [PP1-17 Ala31 Aib32]NPY (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ala31 Aib32]NPY (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ala31 Aib32]NPY (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(20-36) (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(20-36) (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(2-36) (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(2-36) (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY-(13-36) (pig) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the NPY-(13-36) (pig) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[3H]NPY Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [3H]NPY ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

NPY2R Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NPY2R from the Pathway Commons Protein-Protein Interactions dataset.

NPY4R Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NPY4R from the Pathway Commons Protein-Protein Interactions dataset.

NPY1R Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NPY1R from the Pathway Commons Protein-Protein Interactions dataset.

NPY5R Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NPY5R from the Pathway Commons Protein-Protein Interactions dataset.