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PAFAH2 Geneplatelet-activating factor acetylhydrolase 2, 40kDa This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008] |
PAFAH2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PAFAH2 from the Pathway Commons Protein-Protein Interactions dataset. |
PAFAH2 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PAFAH2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |