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PEX14 Geneperoxisomal biogenesis factor 14 This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008] |
pex14 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term pex14 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PEX14 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PEX14 from the Pathway Commons Protein-Protein Interactions dataset. |
PEX14 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PEX14 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
PEX14 homodimer complex Gene Setproteins in the PEX14 homodimer complex protein complex from the CORUM Protein Complexes dataset. |