| Name |
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PPP3CA Geneprotein phosphatase 3, catalytic subunit, alpha isozyme Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; negative regulation of angiotensin-activated signaling pathway; and peptidyl-serine dephosphorylation. Located in cytoplasm; cytoplasmic side of plasma membrane; and dendritic spine. Part of calcineurin complex. Implicated in developmental and epileptic encephalopathy 91. Biomarker of cholangiocarcinoma; focal segmental glomerulosclerosis; and schizophrenia. [provided by Alliance of Genome Resources, Mar 2025] |
PPP3CA Gene SetFrom DEPOD Substrates of Phosphatases substrates of the phosphatase PPP3CA from the curated DEPOD Substrates of Phosphatases dataset. |
ppp3ca Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ppp3ca in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PPP3CA Gene SetFrom NURSA Protein-Protein Interactions interacting proteins for PPP3CA from the NURSA Protein-Protein Interactions dataset. |
PPP3CA Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PPP3CA from the Pathway Commons Protein-Protein Interactions dataset. |
PPP3CA Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the PPP3CA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
PPP3CA Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PPP3CA gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
PPP3CA-PPP3CA-RCAN1 complex Gene Setproteins in the PPP3CA-PPP3CA-RCAN1 complex protein complex from the CORUM Protein Complexes dataset. |
BL3924 (PPP3CA) Gene Setproteins in the BL3924 (PPP3CA) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
BL3927 (PPP3CA) Gene Setproteins in the BL3927 (PPP3CA) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |