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PRRX2 Genepaired related homeobox 2 The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008] |
PRRX2-AS1 GenePRRX2 antisense RNA 1 |
PRRX2 Gene SetFrom JASPAR Predicted Transcription Factor Targets target genes of the PRRX2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. |
PRRX2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PRRX2 from the Pathway Commons Protein-Protein Interactions dataset. |
PRRX2 Gene SetFrom JASPAR Predicted Human Transcription Factor Targets 2025 target genes of the PRRX2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. |
PRRX2 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PRRX2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |