| Name |
|---|
PUF60 Genepoly-U binding splicing factor 60KDa This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] |
puf60 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term puf60 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PUF60 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PUF60 from the Pathway Commons Protein-Protein Interactions dataset. |
PUF60 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PUF60 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |