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PNPO Genepyridoxamine 5'-phosphate oxidase The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq, Oct 2008] |
Pyridoxamine Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical Pyridoxamine from the curated CTD Gene-Chemical Interactions dataset. |
pyridoxamine Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term pyridoxamine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Pyridoxamine Gene SetFrom HMDB Metabolites of Enzymes interacting proteins for the Pyridoxamine metabolite from the curated HMDB Metabolites of Enzymes dataset. |
Pyridoxamine Gene SetFrom MW Enzyme Metabolite Associations interacting proteins for Pyridoxamine metabolite from the MW Gene Metabolite Associations dataset. |
PYRIDOXAMINE Gene Setinteracting proteins for the PYRIDOXAMINE drug from theDGIdb Drug Targets 2026 dataset. |