Harmonizome 3.0

marker of proliferation Ki-67

Enables RNA binding activity and molecular condensate scaffold activity. Involved in chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Is active in condensed chromosome. Implicated in several diseases, including Crohn's disease; colorectal cancer; endocrine gland cancer (multiple); graft-versus-host disease; and human immunodeficiency virus infectious disease. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple); endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and lung cancer (multiple). [provided by Alliance of Genome Resources, Mar 2025]

nucleolar protein interacting with the FHA domain of MKI67

This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.[provided by RefSeq, Jan 2009]

nucleolar protein interacting with the FHA domain of MKI67 pseudogene

nucleolar protein interacting with the FHA domain of MKI67 pseudogene 1

nucleolar protein interacting with the FHA domain of MKI67 pseudogene 2

nucleolar protein interacting with the FHA domain of MKI67 pseudogene 3

nucleolar protein interacting with the FHA domain of MKI67 pseudogene 4

nucleolar protein interacting with the FHA domain of MKI67 pseudogene 5

nucleolar protein interacting with the FHA domain of MKI67 pseudogene 6

nucleolar protein interacting with the FHA domain of MKI67 pseudogene 8

From NURSA Protein Complexes

proteins in the SC-15402 (MKI67) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mki67 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for MKI67 from the MSigDB Cancer Gene Co-expression Modules dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for MKI67 from the Pathway Commons Protein-Protein Interactions dataset.

From CellMarker Gene-Cell Type Associations

genes associated with the MKI67+ T cell_Bile duct_Human cell type from the CellMarker Gene-Cell Type Associations dataset.

From CellMarker Gene-Cell Type Associations

genes associated with the MKI67+ progenitor cell_Large intestine_Human cell type from the CellMarker Gene-Cell Type Associations dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MKI67 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.