Name

SLC22A18 Gene

solute carrier family 22, member 18

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2015]

slc22a18 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term slc22a18 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SLC22A18 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SLC22A18 from the Pathway Commons Protein-Protein Interactions dataset.

SLC22A18 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the SLC22A18 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

Human - Motor Cortex - Cluster - THEMIS+ SLC22A18+ Layer 5 glutamatergic neuron Gene Set

From HuBMAP Azimuth Cell Type Annotations

genes associated with the Human - Motor Cortex - Cluster - THEMIS+ SLC22A18+ Layer 5 glutamatergic neuron cell type from the HuBMAP Azimuth Cell Type Annotations dataset.

Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1) Gene Set

From Reactome Pathways 2024

proteins participating in the Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1) pathway from the Reactome Pathways 2024 dataset.

Brain_CT2_Exc L5 THEMIS SLC22A18 Gene Set

From HuBMAP ASCT+B Annotations

biomarker genes for the Brain_CT2_Exc L5 THEMIS SLC22A18 cell type from the HuBMAP ASCT+B dataset.

Brain_CT2_Exc L5 THEMIS SLC22A18 Gene Set

From HuBMAP ASCT+B Augmented with RNA-seq Coexpression

biomarker genes for the Brain_CT2_Exc L5 THEMIS SLC22A18 cell type from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.