Harmonizome 3.0

structural maintenance of chromosomes 2

Predicted to enable chromatin binding activity. Involved in mitotic chromosome condensation and positive regulation of chromosome condensation. Located in condensed chromosome; cytoplasm; and nuclear lumen. Part of condensin complex. Implicated in colon adenocarcinoma. Biomarker of colorectal cancer. [provided by Alliance of Genome Resources, Mar 2025]

SMC2 antisense RNA 1 (head to head)

SMC2 divergent transcript

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for SMC2 from the MSigDB Cancer Gene Co-expression Modules dataset.

From NURSA Protein-Protein Interactions

interacting proteins for SMC2 from the NURSA Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for SMC2 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the SMC2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Structural maintenance of chromosomes Smc2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From NURSA Protein Complexes

proteins in the BL551 (SMC2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.