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SOAT2 Genesterol O-acyltransferase 2 Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008] |
soat2 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term soat2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
SOAT2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for SOAT2 from the Pathway Commons Protein-Protein Interactions dataset. |
SOAT2 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the SOAT2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |