Name

SP140 Gene

SP140 nuclear body protein

This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]

SP140 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SP140 from the Pathway Commons Protein-Protein Interactions dataset.

SP140 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the SP140 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

SP140 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the SP140 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

Nuclear body protein SP140 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Nuclear body protein SP140 protein domain from the InterPro Predicted Protein Domain Annotations dataset.