Harmonizome 3.0

sorcin

This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene. [provided by RefSeq, Mar 2012]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sri in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for SRI from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the SRI gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the SRI homodimer complex protein complex from the CORUM Protein Complexes dataset.

From DrugBank Drug Targets

interacting proteins for the Sri-9439 drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the Sri-9662 drug from the curated DrugBank Drug Targets dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the SRI, Set2 Rpb1 interacting protein domain from the InterPro Predicted Protein Domain Annotations dataset.