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SSH3 Geneslingshot protein phosphatase 3 The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008] |
SSH3 Gene SetFrom DEPOD Substrates of Phosphatases substrates of the phosphatase SSH3 from the curated DEPOD Substrates of Phosphatases dataset. |
ssh3 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ssh3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
SSH3 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for SSH3 from the Pathway Commons Protein-Protein Interactions dataset. |
SSH3 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the SSH3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |