Name

TADA2A Gene

transcriptional adaptor 2A

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009]

TADA2A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TADA2A from the Pathway Commons Protein-Protein Interactions dataset.

TADA2A Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the TADA2A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

TADA2A Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the TADA2A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.