Name

TGFBR3 Gene

transforming growth factor, beta receptor III

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]

tgfbr3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tgfbr3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

TGFBR3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TGFBR3 from the Pathway Commons Protein-Protein Interactions dataset.

TGFBR3 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the TGFBR3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

Signaling by TGFBR3 Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by TGFBR3 pathway from the Reactome Pathways 2024 dataset.

TGFBR3 PTM regulation Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR3 PTM regulation pathway from the Reactome Pathways 2024 dataset.

TGFBR3 expression Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR3 expression pathway from the Reactome Pathways 2024 dataset.

TGFBR3 regulates FGF2 signaling Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR3 regulates FGF2 signaling pathway from the Reactome Pathways 2024 dataset.

TGFBR3 regulates TGF-beta signaling Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR3 regulates TGF-beta signaling pathway from the Reactome Pathways 2024 dataset.

TGFBR3 regulates activin signaling Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR3 regulates activin signaling pathway from the Reactome Pathways 2024 dataset.