| Name |
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TPX2 GeneTPX2, microtubule-associated Enables importin-alpha family protein binding activity; molecular adaptor activity; and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; nucleoplasm; and spindle. Is active in spindle. [provided by Alliance of Genome Resources, Mar 2025] |
tpx2 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term tpx2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
TPX2 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the TPX2 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
TPX2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for TPX2 from the Pathway Commons Protein-Protein Interactions dataset. |
TPX2 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the TPX2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
TPX2 central domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the TPX2 central domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
TPX2, C-terminal domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the TPX2, C-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
AURKA Activation by TPX2 Gene Setproteins participating in the AURKA Activation by TPX2 pathway from the Reactome Pathways 2024 dataset. |