Harmonizome 3.0

vacuolar protein sorting 29 homolog (S. cerevisiae)

This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term vps29 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for VPS29 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the VPS29 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the Vps29-Vps35-Vps26a complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the VPS35-VPS29-VPS26A complex protein complex from the CORUM Protein Complexes dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphodiesterase MJ0936/Vps29 protein domain from the InterPro Predicted Protein Domain Annotations dataset.