Harmonizome 3.0

vesicle transport through interaction with t-SNAREs 1A

The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term vti1a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for VTI1A from the Pathway Commons Protein-Protein Interactions dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the syntaxin-6-syntaxin-16-vti1a complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From CORUM Protein Complexes

proteins in the SNARE complex (VAMP4, STX6, STX16, VTI1a, VTI1b) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the SNARE complex (VAMP3, STX6, VTI1A) protein complex from the CORUM Protein Complexes dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the syntaxin-6-syntaxin-16-Vti1a complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.