bmal1

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Results for "bmal1": 1 gene, 4 gene sets

Name
BMAL1 Gene basic helix-loop-helix ARNT like 1 The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection, including COVID-19. [provided by RefSeq, Oct 2021]
bmal1 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term bmal1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
BMAL1 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the BMAL1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
BMAL1:CLOCK,NPAS2 activates circadian gene expression Gene Set From Reactome Pathways 2014 proteins participating in the BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway from the Reactome Pathways dataset.
BMAL1:CLOCK,NPAS2 activates circadian gene expression Gene Set From Reactome Pathways 2024 proteins participating in the BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway from the Reactome Pathways 2024 dataset.