Harmonizome 3.0

late cornified envelope 5A

Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 6A

Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 2C

Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 2B

This gene is one of the at least 20 genes expressed during epidermal differentiation and located on chromosomal band 1q21. This gene is involved in epidermal differentiation, and it is expressed at high levels in normal and psoriatic skin, but not in cultured keratinocytes or in any other tested cell types or tissues. [provided by RefSeq, Jul 2008]

late cornified envelope 2A

Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 2D

Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 4A

Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope pseudogene 4

late cornified envelope pseudogene 1

late cornified envelope pseudogene 3

late cornified envelope pseudogene 2

late cornified envelope 1F

Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 1D

Enables identical protein binding activity. Involved in cognition. Acts upstream of or within cellular response to calcium ion. Located in cornified envelope and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 1E

Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 1B

Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 1C

Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 1A

LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 [PubMed 15854049]). For further information on the LCE gene cluster, see GENE FAMILY below.[supplied by OMIM, Feb 2009]

late cornified envelope-like proline-rich 1

late cornified envelope 3D

Predicted to be involved in keratinization. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 3E

Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 3A

Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and killing of cells of another organism. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 3B

Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and killing of cells of another organism. [provided by Alliance of Genome Resources, Mar 2025]

late cornified envelope 3C

Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and killing of cells of another organism. [provided by Alliance of Genome Resources, Mar 2025]

loricrin cornified envelope precursor protein

This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq, Jul 2008]

late cornified envelope 7A

Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Mar 2025]