Harmonizome 3.0

methylmalonyl CoA mutase

This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]

methylmalonyl CoA epimerase

The product of this gene catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria. [provided by RefSeq, Jul 2008]

methylmalonyl-CoA mutase

This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]

From HMDB Metabolites of Enzymes

interacting proteins for the Methylmalonyl-CoA metabolite from the curated HMDB Metabolites of Enzymes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term methylmalonyl in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From PANTHER Pathways

proteins participating in the Methylmalonyl pathway pathway from the PANTHER Pathways dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Methylmalonyl-Coenzyme A Mutase Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From GO Biological Process Annotations 2023

genes participating in the propionate metabolic process, methylmalonyl pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2025

genes participating in the propionate metabolic process, methylmalonyl pathway biological process from the curated GO Biological Process Annotations 2025 dataset.