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MRC1 Genemannose receptor, C type 1 The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015] |
mrc1 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term mrc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
MRC1 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for MRC1 from the Pathway Commons Protein-Protein Interactions dataset. |
MRC1 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the MRC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |