Name

MRC1 Gene

mannose receptor, C type 1

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

mrc1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mrc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MRC1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MRC1 from the Pathway Commons Protein-Protein Interactions dataset.

MRC1 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the MRC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.