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PEA15 Genephosphoprotein enriched in astrocytes 15 This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
pea15 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term pea15 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PEA15 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PEA15 from the Pathway Commons Protein-Protein Interactions dataset. |
PEA15 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PEA15 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |