Gene signatures

Signatures (446) and Custom Report Builder
Title Organism Platform
1 Age effect on lipopolysaccharide-induced neuroinflammation and sickness behavior Mus musculus Mus musculus
2 Age effect on lipopolysaccharide-induced neuroinflammation and sickness behavior Mus musculus Mus musculus
3 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
4 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
5 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
6 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
7 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
8 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
9 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
10 Fisher 344 rat model of aging: parietal cortex Rattus norvegicus Rattus norvegicus
11 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
12 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
13 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
14 Transmembrane protein 88 depletion effect on stem cell cardiac differentiation in vitro Homo sapiens Homo sapiens
15 Transmembrane protein 88 depletion effect on stem cell cardiac differentiation in vitro Homo sapiens Homo sapiens
16 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
17 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
18 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
19 Cardiac aging Rattus norvegicus Rattus norvegicus
20 Vitamin E supplementation effect on aged heart Mus musculus Mus musculus
21 Vitamin E supplementation effect on aged brain Mus musculus Mus musculus
22 Age effect on healing femoral fractures: time course Rattus norvegicus Rattus norvegicus
23 Age effect on healing femoral fractures: time course Rattus norvegicus Rattus norvegicus
24 Age effect on healing femoral fractures: time course Rattus norvegicus Rattus norvegicus
25 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
26 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
27 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
28 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
29 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
30 Caloric restriction effect on the aged heart and adipose tissue Rattus norvegicus Rattus norvegicus
31 Caloric restriction effect on the aged heart and adipose tissue Rattus norvegicus Rattus norvegicus
32 Desmin deficiency effect on young and adult skeletal muscles Mus musculus Mus musculus
33 Mdr2 knockout model of hepatocellular carcinoma at precancerous stages Mus musculus Mus musculus
34 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 4) Homo sapiens Homo sapiens
35 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 4) Homo sapiens Homo sapiens
36 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 4) Homo sapiens Homo sapiens
37 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 4) Homo sapiens Homo sapiens
38 Epigenetic determinants of muscle stem cell quiescence and chronological aging Mus musculus Mus musculus
39 Age-related changes in gene expression in retinal microglia Mus musculus Mus musculus
40 Age-related changes in gene expression in retinal microglia Mus musculus Mus musculus
41 Age-related changes in gene expression in retinal microglia Mus musculus Mus musculus
42 Age-related changes in gene expression in retinal microglia Mus musculus Mus musculus
43 Age-related changes in gene expression in retinal microglia Mus musculus Mus musculus
44 Age-related changes in gene expression in retinal microglia Mus musculus Mus musculus
45 Streptozotocin-induced diabetic model with acute myocardial infarction: time course Rattus norvegicus Rattus norvegicus
46 Host Age is a Systemic Regulator of Gene Expression Impacting Cancer Progression Mus musculus Mus musculus
47 Host Age is a Systemic Regulator of Gene Expression Impacting Cancer Progression Mus musculus Mus musculus
48 Host Age is a Systemic Regulator of Gene Expression Impacting Cancer Progression Mus musculus Mus musculus
49 Host Age is a Systemic Regulator of Gene Expression Impacting Cancer Progression Mus musculus Mus musculus
50 Host Age is a Systemic Regulator of Gene Expression Impacting Cancer Progression Mus musculus Mus musculus
51 Host Age is a Systemic Regulator of Gene Expression Impacting Cancer Progression Mus musculus Mus musculus
52 Mitochondrial gene expression decline in aging is tissue-specific and independent of mitochondrial number Mus musculus Mus musculus
53 Effects of Aging and Anatomic Location on Gene Expression in Human Retina Homo sapiens Homo sapiens
54 Effects of Aging and Anatomic Location on Gene Expression in Human Retina Homo sapiens Homo sapiens
55 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
56 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
57 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
58 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
59 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
60 Analysis of the gene expression within the cochlea of aging C57BL6j mice. Mus musculus Mus musculus
61 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
62 Expression data from tail skin in young (5 months) and old (30 months) CB6F1 mice Mus musculus Mus musculus
63 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
64 Analysis of the gene expression within the cochlea of aging C57BL6j mice. Mus musculus Mus musculus
65 Expression data from tail skin in young (5 months) and old (30 months) CB6F1 mice Mus musculus Mus musculus
66 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
67 Analysis of the gene expression within the cochlea of aging C57BL6j mice. Mus musculus Mus musculus
68 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
69 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
70 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
71 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
72 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
73 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
74 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
75 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
76 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
77 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
78 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
79 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
80 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
81 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
82 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
83 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
84 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
85 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
86 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
87 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
88 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 3) Homo sapiens Homo sapiens
89 Gene Expression Data in Human Monocyte-derived Dendritic Cell (MoDC) from Young and Aged Donors Homo sapiens Homo sapiens
90 P38 signaling underlies a cell-autonomous loss of stem cell self-renewal in aged muscle Mus musculus Mus musculus
91 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
92 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
93 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
94 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
95 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
96 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
97 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
98 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
99 Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle Mus musculus Mus musculus
100 Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle Mus musculus Mus musculus
101 Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle Mus musculus Mus musculus
102 Neural retina leucine zipper deficiency effect on retinas: time course Mus musculus Mus musculus
103 Neural retina leucine zipper deficiency effect on retinas: time course Mus musculus Mus musculus
104 Neural retina leucine zipper deficiency effect on retinas: time course Mus musculus Mus musculus
105 Early events in of DBA/2J model of glaucoma Mus musculus Mus musculus
106 Fracture healing timecourse and the effect of age Rattus norvegicus Rattus norvegicus
107 Fracture healing timecourse and the effect of age Rattus norvegicus Rattus norvegicus
108 Glycine receptor beta subunit mutant model for hyperekplexia Mus musculus Mus musculus
109 Glycine receptor beta subunit mutant model for hyperekplexia Mus musculus Mus musculus
110 Glycine receptor beta subunit mutant model for hyperekplexia Mus musculus Mus musculus
111 Age-related gene expression changes in mouse neocortex Mus musculus Mus musculus
112 Effect of age on the arthritis susceptibility of BALB/c mice Mus musculus Mus musculus
113 Effect of age on the arthritis susceptibility of BALB/c mice Mus musculus Mus musculus
114 Effect of BDNF on aging-related gene expression changes in young and aged rats Rattus norvegicus Rattus norvegicus
115 Effect of BDNF on aging-related gene expression changes in young and aged rats Rattus norvegicus Rattus norvegicus
116 Gene expression profiling in differential cognitive outcomes in aging: CA3 Rattus norvegicus Rattus norvegicus
117 Altered ovarian gene expression in the lethal yellow mouse Mus musculus Mus musculus
118 Altered ovarian gene expression in the lethal yellow mouse Mus musculus Mus musculus
119 Aging of Human Fibroblast Homo sapiens Homo sapiens
120 Aging of Human Fibroblast Homo sapiens Homo sapiens
121 Aging of Human Fibroblast Homo sapiens Homo sapiens
122 Age-related para-inflammation in the neuroretina of the mouse Mus musculus Mus musculus
123 Expression data from aged, calorically restricted rat hippocampal regions CA1, CA3, and DG Rattus norvegicus Rattus norvegicus
124 Expression data from aged, calorically restricted rat hippocampal regions CA1, CA3, and DG Rattus norvegicus Rattus norvegicus
125 Expression data from aged, calorically restricted rat hippocampal regions CA1, CA3, and DG Rattus norvegicus Rattus norvegicus
126 Expression data from aged, calorically restricted rat hippocampal regions CA1, CA3, and DG Rattus norvegicus Rattus norvegicus
127 Expression data from aged, calorically restricted rat hippocampal regions CA1, CA3, and DG Rattus norvegicus Rattus norvegicus
128 Expression data from aged, calorically restricted rat hippocampal regions CA1, CA3, and DG Rattus norvegicus Rattus norvegicus
129 TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression Homo sapiens Homo sapiens
130 TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression Homo sapiens Homo sapiens
131 TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression Homo sapiens Homo sapiens
132 TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression Homo sapiens Homo sapiens
133 TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression Homo sapiens Homo sapiens
134 TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression Homo sapiens Homo sapiens
135 Expression data from mouse bone marrow adipocytes with age Mus musculus Mus musculus
136 Expression data from mouse bone marrow adipocytes with age Mus musculus Mus musculus
137 Expression data from mouse bone marrow adipocytes with age Mus musculus Mus musculus
138 Expression data from mouse bone marrow adipocytes with age Mus musculus Mus musculus
139 Expression data from mouse bone marrow adipocytes with age Mus musculus Mus musculus
140 Expression data from mouse bone marrow adipocytes with age Mus musculus Mus musculus
141 Peroxisome proliferator-γ coactivator-1α deficiency effect on aged gastrocnemius muscle Mus musculus Mus musculus
142 Age effect on the hippocampus Mus musculus Mus musculus
143 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
144 Anti-TB chemotherapy effect on peripheral blood mononuclear cells from active tuberculosis patients: time course Homo sapiens Homo sapiens
145 Anti-TB chemotherapy effect on peripheral blood mononuclear cells from active tuberculosis patients: time course Homo sapiens Homo sapiens
146 Lung response to thoracic irradiation: dose response and time course Mus musculus Mus musculus
147 Lung response to thoracic irradiation: dose response and time course Mus musculus Mus musculus
148 Lung response to thoracic irradiation: dose response and time course Mus musculus Mus musculus
149 Blood from septic patients: time course Homo sapiens Homo sapiens
150 Blood from septic patients: time course Homo sapiens Homo sapiens
151 Blood from septic patients: time course Homo sapiens Homo sapiens
152 Blood from septic patients: time course Homo sapiens Homo sapiens
153 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
154 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
155 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
156 Young and aged skeletal muscles response to long-term vigorous endurance exercise Homo sapiens Homo sapiens
157 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
158 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
159 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
160 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
161 Caloric restriction effect on aged skeletal muscle Mus musculus Mus musculus
162 Age effect on the hippocampus Mus musculus Mus musculus
163 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
164 Age effect on hematopoietic stem cells Mus musculus Mus musculus
165 Hutchinson-Gilford progeria syndrome: fibroblast (HG-U133B) Homo sapiens Homo sapiens
166 Age effect on lipopolysaccharide-induced neuroinflammation and sickness behavior Mus musculus Mus musculus
167 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
168 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
169 Age effect on myoblast progenitors Mus musculus Mus musculus
170 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
171 Muscle function and aging - female (HG-U133B) Homo sapiens Homo sapiens
172 Cardiac aging Rattus norvegicus Rattus norvegicus
173 Muscle function and aging - male (HG-U133B) Homo sapiens Homo sapiens
174 Gene expression of young and old mice Mus musculus Mus musculus
175 Transcriptome analysis of aging muscle progenitors (human myoblasts) Homo sapiens Homo sapiens
176 Transcriptome analysis of aging muscle progenitors (human myoblasts) Homo sapiens Homo sapiens
177 Expression data from young and old healthy humans, as well as HGPS patients Homo sapiens Homo sapiens
178 Peroxisome proliferator-γ coactivator-1α deficiency effect on aged gastrocnemius muscle Mus musculus Mus musculus
179 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
180 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
181 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
182 Age effect on myoblast progenitors Mus musculus Mus musculus
183 Hepatic gene expression changes in aging and R-α-lipoic acid supplementation: Necroinflammatory phenotype, lipid synthesis regulation and circadian rhythms. Rattus norvegicus Rattus norvegicus
184 Age-dependent decline in lung regeneration with loss of clonogenicity and myofibroblastic differentiation of lung fibroblasts Mus musculus Mus musculus
185 Hippocampal gene expression in aged and young HSD1 knockout mice Mus musculus Mus musculus
186 Hippocampal gene expression changes during age-related cognitive decline Mus musculus Mus musculus
187 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
188 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
189 Amyotrophic lateral sclerosis model Mus musculus Mus musculus
190 Huntington disease model: brain striatum (430 2.0) Mus musculus Mus musculus
191 Huntington's disease transgenic model: time course Mus musculus Mus musculus
192 Huntington's disease transgenic model: time course Mus musculus Mus musculus
193 Huntington's disease transgenic model: time course Mus musculus Mus musculus
194 Gene expression profile of N171-HD82Q hippocampus and cerebellum. Mus musculus Mus musculus
195 Expression data from 9 and 13 weeks old TIFIAD1Cre mice Mus musculus Mus musculus
196 Moderate stage Huntington's disease lymphocytes Homo sapiens Homo sapiens
197 Striatal gene expression data from 3- and 18-month-old Q92 mice and control mice. Mus musculus Mus musculus
198 Nuclear and extranuclear mutant huntingtin exon 1 protein effect on cerebellum Mus musculus Mus musculus
199 Nuclear and extranuclear mutant huntingtin exon 1 protein effect on cerebellum Mus musculus Mus musculus
200 Nuclear and extranuclear mutant huntingtin exon 1 protein effect on cerebellum Mus musculus Mus musculus
201 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
202 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
203 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
204 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
205 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
206 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
207 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
208 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
209 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
210 Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth Mus musculus Mus musculus
211 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
212 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
213 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
214 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
215 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
216 Age-related gene expression changes in mouse neocortex Mus musculus Mus musculus
217 Nuclear and extranuclear mutant huntingtin exon 1 protein effect on cerebellum Mus musculus Mus musculus
218 Gene expression profile of N171-HD82Q hippocampus and cerebellum. Mus musculus Mus musculus
219 Huntington's disease transgenic model: time course Mus musculus Mus musculus
220 Hippocampal gene expression changes during age-related cognitive decline Mus musculus Mus musculus
221 Hippocampal gene expression in aged and young HSD1 knockout mice Mus musculus Mus musculus
222 Peroxisome proliferator-γ coactivator-1α deficiency effect on aged gastrocnemius muscle Mus musculus Mus musculus
223 Age effect on skeletal muscle precursor cells Mus musculus Mus musculus
224 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
225 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
226 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
227 Premature Hematopoietic Aging model: bone marrow hematopoietic stem cells Mus musculus Mus musculus
228 Aging effect on bone marrow hematopoietic stem cells Homo sapiens Homo sapiens
229 Fisher 344 rat model of aging: parietal cortex Rattus norvegicus Rattus norvegicus
230 Induced pluripotent stem cell-based accelerated aging model Homo sapiens Homo sapiens
231 Caloric restriction effect on the aged heart and adipose tissue Rattus norvegicus Rattus norvegicus
232 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
233 Aging lungs and genetic background Mus musculus Mus musculus
234 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
235 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
236 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
237 Age effect on hematopoietic stem cells Mus musculus Mus musculus
238 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
239 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
240 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
241 Age effect on myoblast progenitors Mus musculus Mus musculus
242 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
243 Muscle function and aging - female (HG-U133B) Homo sapiens Homo sapiens
244 Cardiac aging Rattus norvegicus Rattus norvegicus
245 Muscle function and aging - male (HG-U133B) Homo sapiens Homo sapiens
246 The effects of aging on circadian patterns of gene expression in the human prefrontal cortex Homo sapiens Homo sapiens
247 The effects of aging on circadian patterns of gene expression in the human prefrontal cortex Homo sapiens Homo sapiens
248 Altered lipid metabolism in the aging kidney identified by three layered omic analysis Mus musculus Mus musculus
249 Gene expression of young and old mice Mus musculus Mus musculus
250 Mitochondrial gene expression decline in aging is tissue-specific and independent of mitochondrial number Mus musculus Mus musculus
251 Transcriptome analysis of aging muscle progenitors (human myoblasts) Homo sapiens Homo sapiens
252 Effects of Aging and Anatomic Location on Gene Expression in Human Retina Homo sapiens Homo sapiens
253 Expression data from aging study on mouse spermatogonial stem/progenitor cell population Mus musculus Mus musculus
254 Expression data from aging study on mouse spermatogonial stem/progenitor cell population Mus musculus Mus musculus
255 Microarray analysis of gene expression in aging in mouse sabmandibular gland. Mus musculus Mus musculus
256 SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1beta Mus musculus Mus musculus
257 SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1beta Mus musculus Mus musculus
258 Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions Mus musculus Mus musculus
259 Functionally distinct subsets of lineage-biased multipotent progenitors control blood production in normal and regenerative conditions Mus musculus Mus musculus
260 Aging-induced differential methylation in human PBMCs occurs with but often without change in expression of the associated gene (Expression) Homo sapiens Homo sapiens
261 REST and Stress Resistance in Aging and Alzheimer’s Disease Homo sapiens Homo sapiens
262 Novel approach to select genes from RMA normalized microarray data using functional hearing tests in aging mice. Mus musculus Mus musculus
263 Rapamycin extends life span, but has limited effects on aging in mice Mus musculus Mus musculus
264 Rapamycin extends life span, but has limited effects on aging in mice Mus musculus Mus musculus
265 Rapamycin extends life span, but has limited effects on aging in mice Mus musculus Mus musculus
266 Epigenetic determinants of muscle stem cell quiescence and chronological aging Mus musculus Mus musculus
267 Transcriptome Analysis of Human Injured Meniscus Reveals a Distinct Phenotype of Meniscus Degeneration with Aging Homo sapiens Homo sapiens
268 An Epigenetic Component of Hematopoietic Stem Cell Aging Amenable to Reprogramming Into a Young State Mus musculus Mus musculus
269 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
270 Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging Mus musculus Mus musculus
271 A systems approach identifies progeroid Ercc1[-/Δ] mice as a model system for kidney aging. Mus musculus Mus musculus
272 Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice Mus musculus Mus musculus
273 Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice Mus musculus Mus musculus
274 Analysis of the gene expression within the cochlea of aging C57BL6j mice. Mus musculus Mus musculus
275 Aging effect on bone marrow hematopoietic stem cells Homo sapiens Homo sapiens
276 The impact of aging on memory T cell phenotype and function in the human bone marrow Homo sapiens Homo sapiens
277 Premature Hematopoietic Aging model: bone marrow hematopoietic stem cells Mus musculus Mus musculus
278 Fisher 344 rat model of aging: parietal cortex Rattus norvegicus Rattus norvegicus
279 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
280 Hepatic gene expression changes in aging and R-α-lipoic acid supplementation: Necroinflammatory phenotype, lipid synthesis regulation and circadian rhythms. Rattus norvegicus Rattus norvegicus
281 The effects of aging vs. alpha7 nAChR subunit deficiency on the mouse brain transcriptome Mus musculus Mus musculus
282 Distinct signature of altered homeostasis in aging rod photoreceptors: Implications for retinal diseases Mus musculus Mus musculus
283 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
284 Aging of Human Fibroblast Homo sapiens Homo sapiens
285 Effect of BDNF on aging-related gene expression changes in young and aged rats Rattus norvegicus Rattus norvegicus
286 Effect of BDNF on aging-related gene expression changes in young and aged rats Rattus norvegicus Rattus norvegicus
287 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
288 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
289 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
290 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
291 Coordinated Changes in Xenobiotic Metabolizing Enzyme Gene Expression in Aging Male Rats: Brown Norway and F344 Rattus norvegicus Rattus norvegicus
292 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
293 Resistance Exercise Reverses Aging in Human Skeletal Muscle Homo sapiens Homo sapiens
294 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
295 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
296 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
297 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
298 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
299 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
300 Transcriptional profile of aging human muscle Homo sapiens Homo sapiens
301 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
302 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
303 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
304 Aging Liver Profiles of the Long Lived Prop-1 Mutant Mouse (Ames) and Wild Type Controls Mus musculus Mus musculus
305 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
306 Age effect on myoblast progenitors Mus musculus Mus musculus
307 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
308 Cardiac aging Rattus norvegicus Rattus norvegicus
309 Age effect on skeletal muscle precursor cells Mus musculus Mus musculus
310 Age effect on skeletal muscle precursor cells Mus musculus Mus musculus
311 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
312 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
313 Desmin deficiency effect on young and adult skeletal muscles Mus musculus Mus musculus
314 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
315 Aging effect on bone marrow hematopoietic stem cells Homo sapiens Homo sapiens
316 Fisher 344 rat model of aging: parietal cortex Rattus norvegicus Rattus norvegicus
317 BPH/J2 model of neurogenic hypertension: hypothalamus Mus musculus Mus musculus
318 Williams-Beuren Syndrome: fibroblast cell lines Homo sapiens Homo sapiens
319 Young and aged skeletal muscles response to long-term vigorous endurance exercise Homo sapiens Homo sapiens
320 Vitamin E supplementation effect on aged heart Mus musculus Mus musculus
321 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
322 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
323 Age effect on the hippocampus Mus musculus Mus musculus
324 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
325 Age effect on hematopoietic stem cells Mus musculus Mus musculus
326 Muscle function and aging - female (HG-U133B) Homo sapiens Homo sapiens
327 Cardiac aging Rattus norvegicus Rattus norvegicus
328 Muscle function and aging - male (HG-U133B) Homo sapiens Homo sapiens
329 Expression data from whole lateral ventricle choroid plexus tissue of young (two months old) and aged (eighteen months old) CD1 male mice. Mus musculus Mus musculus
330 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
331 Altered lipid metabolism in the aging kidney identified by three layered omic analysis Mus musculus Mus musculus
332 Effects of Aging and Anatomic Location on Gene Expression in Human Retina Homo sapiens Homo sapiens
333 Effects of Aging and Anatomic Location on Gene Expression in Human Retina Homo sapiens Homo sapiens
334 Mitochondrial gene expression decline in aging is tissue-specific and independent of mitochondrial number Mus musculus Mus musculus
335 Microarray analysis of gene expression in aging in mouse sabmandibular gland. Mus musculus Mus musculus
336 Transcriptome analysis of aging muscle progenitors (human myoblasts) Homo sapiens Homo sapiens
337 Transcriptome analysis of aging muscle progenitors (human myoblasts) Homo sapiens Homo sapiens
338 Host Age is a Systemic Regulator of Gene Expression Impacting Cancer Progression Mus musculus Mus musculus
339 Age-associated Changes in Basal NF-κB Function in Human CD4+ T Lymphocytes via Dysregulation of PI3 Kinase (dataset 5) Homo sapiens Homo sapiens
340 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
341 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
342 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
343 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
344 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
345 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
346 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
347 Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration Mus musculus Mus musculus
348 Age-mediated transcriptomic changes in adult mouse brain ventral tegmental area Mus musculus Mus musculus
349 Age-mediated transcriptomic changes in adult mouse substantia nigra Mus musculus Mus musculus
350 P38 signaling underlies a cell-autonomous loss of stem cell self-renewal in aged muscle Mus musculus Mus musculus
351 Hippocampal Gene Expression in Young and Adult Mice with Memory Deficits Mus musculus Mus musculus
352 Hippocampal Gene Expression in Young and Adult Mice with Memory Deficits Mus musculus Mus musculus
353 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
354 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
355 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
356 Age effect on laryngeal muscle Rattus norvegicus Rattus norvegicus
357 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
358 Age effect on livers of long-lived Snell dwarf mutants Mus musculus Mus musculus
359 Age effect on myoblast progenitors Mus musculus Mus musculus
360 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
361 Aging lungs and genetic background Mus musculus Mus musculus
362 Aging lungs and genetic background Mus musculus Mus musculus
363 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
364 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
365 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
366 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
367 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
368 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
369 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
370 Alzheimer's Disease Dataset Homo sapiens Homo sapiens
371 Analysis of the gene expression within the cochlea of aging C57BL6j mice. Mus musculus Mus musculus
372 Caloric restriction effect on the aged heart and adipose tissue Rattus norvegicus Rattus norvegicus
373 Caloric restriction effect on the aged heart and adipose tissue Rattus norvegicus Rattus norvegicus
374 Age effect on normal adult brain: frontal cortical region Homo sapiens Homo sapiens
375 Age effect on normal adult brain: frontal cortical region Homo sapiens Homo sapiens
376 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
377 Fisher 344 rat model of aging: parietal cortex Rattus norvegicus Rattus norvegicus
378 BPH/J2 model of neurogenic hypertension: hypothalamus Mus musculus Mus musculus
379 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
380 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
381 Age effect on the hippocampus Mus musculus Mus musculus
382 Age effect on lipopolysaccharide-induced neuroinflammation and sickness behavior Mus musculus Mus musculus
383 Alpha-synuclein deficiency effect on striatum and cerebellum: time course Mus musculus Mus musculus
384 Hippocampal gene expression in aged and young HSD1 knockout mice Mus musculus Mus musculus
385 Alpha-synuclein deficiency effect on striatum and cerebellum: time course Mus musculus Mus musculus
386 Regional commonalities and specificities of age-related changes in hippocampal transcriptome. Rattus norvegicus Rattus norvegicus
387 Regional commonalities and specificities of age-related changes in hippocampal transcriptome. Rattus norvegicus Rattus norvegicus
388 Age-mediated transcriptomic changes in adult mouse substantia nigra and ventral tegmental area Mus musculus Mus musculus
389 Regional commonalities and specificities of age-related changes in hippocampal transcriptome. Rattus norvegicus Rattus norvegicus
390 Age-mediated transcriptomic changes in adult mouse substantia nigra and ventral tegmental area Mus musculus Mus musculus
391 Analysis of hippocampal gene expression in adult and aged male BABL/c mice with or without running wheel access Mus musculus Mus musculus
392 Age-mediated transcriptomic changes in adult mouse substantia nigra and ventral tegmental area Mus musculus Mus musculus
393 Age-mediated transcriptomic changes in adult mouse substantia nigra and ventral tegmental area Mus musculus Mus musculus
394 Fisher 344 rat model of aging: parietal cortex Rattus norvegicus Rattus norvegicus
395 The effects of aging vs. alpha7 nAChR subunit deficiency on the mouse brain transcriptome Mus musculus Mus musculus
396 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
397 Altered gene expression is associated with age-dependent memory impairment Mus musculus Mus musculus
398 Coenzyme Q10-dependent gene expression in SAMP1 mice tissues Mus musculus Mus musculus
399 Effect of BDNF on aging-related gene expression changes in young and aged rats Rattus norvegicus Rattus norvegicus
400 Hippocampal gene expression changes during age-related cognitive decline Mus musculus Mus musculus
401 Effect of BDNF on aging-related gene expression changes in young and aged rats Rattus norvegicus Rattus norvegicus
402 Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle Mus musculus Mus musculus
403 Brain_Aging mouse mouse
404 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
405 Age effect on the hippocampus Mus musculus Mus musculus
406 Age effect on lipopolysaccharide-induced neuroinflammation and sickness behavior Mus musculus Mus musculus
407 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
408 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
409 Progranulin deficiency effect on various brain regions: time course Mus musculus Mus musculus
410 Progranulin deficiency effect on various brain regions: time course Mus musculus Mus musculus
411 Progranulin deficiency effect on various brain regions: time course Mus musculus Mus musculus
412 Progranulin deficiency effect on various brain regions: time course Mus musculus Mus musculus
413 Schizophrenia: postmortem anterior prefrontal cortex Homo sapiens Homo sapiens
414 Schizophrenia: postmortem superior temporal cortex Homo sapiens Homo sapiens
415 Huntington disease model: brain striatum (430 2.0) Mus musculus Mus musculus
416 Spinocerebellar ataxia type 1 knock-in model: cerebellum Mus musculus Mus musculus
417 Visual cortex during the critical period for ocular dominance (MG-U74A) Mus musculus Mus musculus
418 Vitamin E supplementation effect on aged brain Mus musculus Mus musculus
419 Prefrontal cortex postnatal development: time course Mus musculus Mus musculus
420 CAG repeat knock-in model of spinocerebellar ataxia type 1 progression Mus musculus Mus musculus
421 CAG repeat knock-in model of spinocerebellar ataxia type 1 progression Mus musculus Mus musculus
422 Pulmonary CDC11c+ cells from young and middle-age animals Mus musculus Mus musculus
423 Age effect on lipopolysaccharide-induced neuroinflammation and sickness behavior Mus musculus Mus musculus
424 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
425 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
426 Thiazolidinedione pioglitazone effect on Fischer 344 model of aging: hippocampus Rattus norvegicus Rattus norvegicus
427 Age effect on extraocular muscles Rattus norvegicus Rattus norvegicus
428 Fisher 344 rat model of aging: parietal cortex Rattus norvegicus Rattus norvegicus
429 Cardiac aging Rattus norvegicus Rattus norvegicus
430 Vitamin E supplementation effect on aged heart Mus musculus Mus musculus
431 Vitamin E supplementation effect on aged brain Mus musculus Mus musculus
432 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
433 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
434 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
435 Hippocampal aging and cognitive impairment Rattus norvegicus Rattus norvegicus
436 Age-related aortic vasculopathy model Rattus norvegicus Rattus norvegicus
437 Desmin deficiency effect on young and adult skeletal muscles Mus musculus Mus musculus
438 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
439 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
440 Skeletal muscles from men and women of various ages Homo sapiens Homo sapiens
441 Young and aged skeletal muscles response to long-term vigorous endurance exercise Homo sapiens Homo sapiens
442 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
443 Model of cerebral aging and Alzheimer's disease: temporal cortex Homo sapiens; Microcebus murinus Homo sapiens; Microcebus murinus
444 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
445 Neurological aging models: retinas and hippocampi Mus musculus Mus musculus
446 Caloric restriction effect on aged skeletal muscle Mus musculus Mus musculus

PCA

Interactive 3D principal component analysis of gene signatures. You can rotate the visualization and mouse over the data points.

Genes

Hierarchical clustering of genes based on weights from the differential expression method.

Enrichr

Enrichr is a web tool that performs gene set enrichment analysis. To generate the hierarchical clusterings below, GEN3VA enriched each gene signature using Enrichr and then clustered the terms. Use the select button to change Enrichr's background library.

Hierarchical clustering of enriched terms from

L1000CDS2

L1000CDS2 is a web tool that queries the LINCS L1000 dataset to identify small molecules that can reverse or mimic the observed input expression pattern. To generate the hierarchical clustering below, GEN3VA enriched each gene signature using L1000CDS2 to generate a list of perturbations that either mimic (red) and reverse (blue) expression.