Harmonizome 3.0

TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)

Enables RNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Mar 2025]

TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)

Enables 18S rRNA aminocarboxypropyltransferase activity. Involved in enzyme-directed rRNA pseudouridine synthesis. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)

The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia. [provided by RefSeq, Oct 2016]

TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) pseudogene

From DGIdb Drug Targets 2026

interacting proteins for the (20S,21S)-FLUOROCAMPTOTHECIN drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the (20S,21S)-7-CYCLOHEXYLFLUOROCAMPTOTHECIN drug from theDGIdb Drug Targets 2026 dataset.

From DrugBank Drug Targets

interacting proteins for the (21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the (3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- drug from the curated DrugBank Drug Targets dataset.

From CORUM Protein Complexes

proteins in the 20S methyltransferase core complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PA28-20S proteasome protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PA28gamma-20S proteasome protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the 20S methylosome-SmD complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the 20S methylosome and RG-containing Sm protein complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the 20S methyltransferase complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PA700-20S-PA28 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the 20S proteasome protein complex from the CORUM Protein Complexes dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical ginsenoside 20S-protopanaxatriol from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical 2-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol from the curated CTD Gene-Chemical Interactions dataset.

From DrugBank Drug Targets

interacting proteins for the (20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the (20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE drug from the curated DrugBank Drug Targets dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the D-site 20S pre-rRNA nuclease Nob1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From MW Enzyme Metabolite Associations

interacting proteins for 20S-Hydroxy-5alpha-pregnan-3-one metabolite from the MW Gene Metabolite Associations dataset.