| Name |
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ATF6B Geneactivating transcription factor 6 beta The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
ATF6B Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for ATF6B from the Pathway Commons Protein-Protein Interactions dataset. |
ATF6B Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the ATF6B gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
ATF6B (ATF6-beta) activates chaperones Gene Setproteins participating in the ATF6B (ATF6-beta) activates chaperones pathway from the Reactome Pathways 2024 dataset. |