Name

ATF6B Gene

activating transcription factor 6 beta

The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

ATF6B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ATF6B from the Pathway Commons Protein-Protein Interactions dataset.

ATF6B Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the ATF6B gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

ATF6B (ATF6-beta) activates chaperones Gene Set

From Reactome Pathways 2024

proteins participating in the ATF6B (ATF6-beta) activates chaperones pathway from the Reactome Pathways 2024 dataset.