Harmonizome 3.0

mastermind-like 1 (Drosophila)

This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]

From NURSA Protein Complexes

proteins in the BL1239 (MAML1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the maml1-rbp-jkappa- icn1 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From CORUM Protein Complexes

proteins in the MAML1-RBP-Jkappa-Notch1 complex protein complex from the CORUM Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term maml1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Cellular Component Annotations 2015

proteins localized to the maml1-rbp-jkappa- icn1 complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From NURSA Protein Complexes

proteins in the BL1238 (MAML1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for MAML1 from the Pathway Commons Protein-Protein Interactions dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the MAML1-RBP-Jkappa- ICN1 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the MAML1-RBP-Jkappa- ICN1 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MAML1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.