Harmonizome 3.0

transmembrane protein 206

Enables pH-gated chloride channel activity. Involved in chloride transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

microRNA 206

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. Disruption of the encoded miRNA has been implicated in multiple skeletal muscle disorders, including amyotrophic lateral sclerosis (ALS) and Duchenne muscular dystrophy (DMD), as well as in several cancers. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Aug 2017]

family with sequence similarity 206, member A

Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in dendrite morphogenesis; regulation of actin filament polymerization; and regulation of filopodium assembly. Predicted to be located in growth cone. Predicted to be active in several cellular components, including dendrite; filopodium tip; and lamellipodium. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 206, member B, pseudogene

cilia and flagella associated protein 206

Predicted to be involved in regulation of cilium beat frequency; regulation of flagellated sperm motility; and sperm axoneme assembly. Predicted to be located in A axonemal microtubule and motile cilium. Predicted to be part of radial spoke. Predicted to be active in axoneme and ciliary basal body. [provided by Alliance of Genome Resources, Mar 2025]

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical CQA 206-291 from the curated CTD Gene-Chemical Interactions dataset.

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the celecoxib-206 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

From MiRTarBase microRNA Targets

target genes of the hsa-miR-206 microRNA in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.

From TargetScan Predicted Conserved microRNA Targets

target genes of the hsa-miR-206 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

From TargetScan Predicted Nonconserved microRNA Targets

target genes of the hsa-miR-206 microRNA predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.

From HuBMAP ASCT+B Annotations

biomarker genes for the Brain_CT2_MSN 206 cell type from the HuBMAP ASCT+B dataset.

From HuBMAP ASCT+B Augmented with RNA-seq Coexpression

biomarker genes for the Brain_CT2_MSN 206 cell type from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC2742312-1479-7364-3-3-221-S3.PDF-206-ZNF248_ZNF248 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC3470785-NIHMS377161-supplement-12.pdf-206-SHOX2_SHOX2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC11130167-41598_2024_60721_MOESM1_ESM.pdf-206-NR3C1_NR3C1 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC12612227-41523_2025_836_MOESM1_ESM.pdf-206-ZNF433_ZNF433 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.