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CXCL10 Genechemokine (C-X-C motif) ligand 10 This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020] |
cxcl10 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term cxcl10 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
CXCL10 Gene SetFrom Guide to Pharmacology Protein Ligands of Receptors receptors of the CXCL10 ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset. |
CXCL10 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for CXCL10 from the Pathway Commons Protein-Protein Interactions dataset. |
CXCL10 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the CXCL10 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
CXCL10 Gene Setinteracting proteins for the CXCL10 drug from theDGIdb Drug Targets 2026 dataset. |
[125I]CXCL10 Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the [125I]CXCL10 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
increased circulating CXCL10 level Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the increased circulating CXCL10 level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
increased CXCL10 level Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the increased CXCL10 level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
decreased circulating CXCL10 level Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased circulating CXCL10 level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
decreased CXCL10 secretion Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased CXCL10 secretion phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
[125I]CXCL10 (HUMAN) Gene Setinteracting proteins for the [125I]CXCL10 (HUMAN) drug from theDGIdb Drug Targets 2026 dataset. |