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CALR Genecalreticulin Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020] |
CALR3 Genecalreticulin 3 The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy. [provided by RefSeq, Dec 2011] |
CALR4P Genecalreticulin 4, pseudogene |
Calreticulin/calnexin Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Calreticulin/calnexin protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Calreticulin/calnexin, P domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Calreticulin/calnexin, P domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Calreticulin/calnexin, conserved site Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Calreticulin/calnexin, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
N-glycan trimming in the ER and Calnexin/Calreticulin cycle Gene Setproteins participating in the N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway from the Reactome Pathways dataset. |
Calnexin/calreticulin cycle Gene Setproteins participating in the Calnexin/calreticulin cycle pathway from the Reactome Pathways dataset. |
Calnexin/calreticulin cycle Gene Setproteins participating in the Calnexin/calreticulin cycle pathway from the Reactome Pathways 2024 dataset. |
N-glycan trimming in the ER and Calnexin/Calreticulin cycle Gene Setproteins participating in the N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway from the Reactome Pathways 2024 dataset. |
calnexin Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term calnexin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Calreticulin oligomer complex Gene Setproteins in the Calreticulin oligomer complex protein complex from the CORUM Protein Complexes dataset. |
calreticulin Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term calreticulin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Calreticulin Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Calreticulin protein domain from the InterPro Predicted Protein Domain Annotations dataset. |