Name

E2F6 Gene

E2F transcription factor 6

This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

E2F6 Gene Set

From ENCODE Transcription Factor Targets

target genes of the E2F6 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

e2f6 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term e2f6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

E2F6 Gene Set

From JASPAR Predicted Transcription Factor Targets

target genes of the E2F6 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

E2F6 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for E2F6 from the Pathway Commons Protein-Protein Interactions dataset.

E2F6 Gene Set

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the E2F6 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

E2F6 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the E2F6 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

Transcription factor E2F6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription factor E2F6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Transcriptional Regulation by E2F6 Gene Set

From Reactome Pathways 2024

proteins participating in the Transcriptional Regulation by E2F6 pathway from the Reactome Pathways 2024 dataset.