Name

KLK2 Gene

kallikrein-related peptidase 2

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]

klk2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term klk2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

KLK2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for KLK2 from the Pathway Commons Protein-Protein Interactions dataset.

Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Gene Set

From Reactome Pathways 2024

proteins participating in the Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 pathway from the Reactome Pathways 2024 dataset.

HK2P01 DERIVATIVE KLK2 INHIBITOR Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the HK2P01 DERIVATIVE KLK2 INHIBITOR drug from theDGIdb Drug Targets 2026 dataset.