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LLGL2 Genelethal giant larvae homolog 2 (Drosophila) The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
LLGL2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for LLGL2 from the Pathway Commons Protein-Protein Interactions dataset. |
LLGL2 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the LLGL2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
LLGL2-PAR-6B-PRKCI complex Gene Setproteins in the LLGL2-PAR-6B-PRKCI complex protein complex from the CORUM Protein Complexes dataset. |