Harmonizome 3.0

MIA-RAB4B readthrough (NMD candidate)

This locus represents naturally occurring read-through transcription between the neighboring MIA (melanoma inhibitory activity) and RAB4B (RAB4B, member RAS oncogene family) genes on chromosome 19. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

melanoma inhibitory activity

Predicted to enable growth factor activity. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within cell-matrix adhesion. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

From COSMIC Cell Line Gene CNV Profiles

genes with high or low copy number in MIA-PACA-2 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

From COSMIC Cell Line Gene Mutation Profiles

genes mutated in the MIA-PACA-2 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

From GDSC Cell Line Gene Expression Profiles

genes with high or low expression in MIA-PaCa-2 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

From Sanger Dependency Map Cancer Cell Line Proteomics

proteins associated with the cell line MIA-PaCa-2 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mia in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for MIA from the Pathway Commons Protein-Protein Interactions dataset.