Harmonizome 3.0

MORC family CW-type zinc finger 2

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

MORC2 antisense RNA 1

From Pathway Commons Protein-Protein Interactions

interacting proteins for MORC2 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MORC2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From NURSA Protein Complexes

proteins in the BL994 (MORC2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From NURSA Protein Complexes

proteins in the BL993 (MORC2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the MORC2-related neurodevelopmental disorders phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.